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Bemiparin sodium interactions with other medicinal products have not been investigated and the information given on this section is derived from data available from other Low Molecular Weight Heparin.
The concomitant administration of bemiparin and the following medicinal products is not advisable: Vitamin K antagonists and other anticoagulants, acetyl salicylic acid and other salicylates and NSAIDs, ticlopidine, clopidogrel and other platelet inhibitors systemic glucocorticoids and dextran.
All these drugs increase the pharmacological effect of bemiparin by interfering with its action on coagulation and/or platelet function and increasing the risk of bleeding.
If the combination cannot be avoided, it should be used with careful clinical and laboratory monitoring.
Medicinal products that increase the serum potassium concentration should only be taken concomitantly under especially careful medical supervision.
Interaction of heparin with intravenous nitroglycerine (which can result in a decrease in efficacy) cannot be ruled out for bemiparin.
